Pharmaceutical Processing

Solid Dosage – Blending and Tablet Handling

The Pharmaceutical Solid Dosage manufacturing process involves mixing API (Active Pharmaceutical Ingredients) with excipients to create solid dosage forms such as powder, granules, tablets, capsules and pellets.

Matcon IBC solutions are widely used in the Solid Dosage industry, where we are able to provide solutions for blending powders within IBCs, handling blended powders without segregation and tablet handling in bulk without damage. As a result we have many successful installations in major blue-chip pharmaceutical companies and in many generic manufacturing companies.

Matcon offers the full range of IBC solutions for the industry, including formulation systems and blenders as well as having the knowledge and experience to successfully interface with granulation, roller compaction, milling, blending, compression, coating, printing and packing.

                    Solid Dosage Industry – Example System Solution

We have considerable experience in providing solutions for:

• Containment (with the ability to achieve containment to less than 1microgram where required)

• Nitrogen Purging

• CIP (Clean In Place)

• Preventing segregation of blended materials

• Gentle handling of delicate materials, such as tablets.

Active Pharmaceutical Ingredients (API)

The Pharmaceutical API manufacturing process commonly involves reaction of powder with solvents, followed by various drying processes.

Matcon’s IBC systems have the unique ability to be able to handle the solvent rich, “wet cake” solids between the centrifuge and drying processes, as well as the powders before reaction and after drying. This enables the contents of any reactor to be transferred to any dryer using IBCs.

It is the ability to discharge the full range of API bulk solids from IBCs in a controlled and contained manner that has made Matcon the choice for many major blue-chip pharmaceutical API companies.

Matcon offers the full range of IBC solutions for the industry, including dispensary systems as well as having the knowledge and experience to successfully interface with reaction, centrifuge, drying, milling, sieving and packing processes.

                    API Industry – Example System Solution 

We have considerable experience in providing solutions for:

• Complete and automatic discharge of solvent rich, “wet cake” solids
• Containment (with the ability to achieve containment to less than 1 microgram where required)
• Nitrogen Purging
• CIP (Clean In Place)